Dual Inhibition of Amyloid Aggregation: A Promising Therapeutic Strategy for Alzheimer’s Disease in the Context of Type 2 Diabetes Mellitus (P12-3.016)
To explore the potential of dual inhibitors targeting both amyloid-β 42 (Aβ42) and islet amyloid polypeptide (IAPP) as a therapeutic approach for treating Alzheimer’s Disease (AD) in patients with Type 2 Diabetes Mellitus (T2DM), addressing the limitations of current treatments that do not effectively target IAPP’s role in AD progression.
Authors
- Rebecca Ryznar
- Pon Velayutham Anandh Babu (ORCID: https://orcid.org/0000-0002-8424-5421)
- Christopher D. Turner (ORCID: https://orcid.org/0000-0003-2348-5373)
Institutions
- Rocky Vista University (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000208581
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00