MICRO: Microsurgical Index for Complication Risk and Outcomes

Free tissue transfer (FTT) is determined by a multitude of patient and surgeon factors. However, no tool exists to quantify patient risk for complications following FTT. This study developed the microsurgical index for complication risk and outcomes (MICRO) to address this.Patients were queried from the 2007 to 2015 MarketScan Databases with CPT codes for FTT requiring microsurgical anastomosis. ICD-9 codes were used to query comorbidity and 90-day postoperative complication data for each patient. The Charlson and Elixhauser Comorbidity Indexes were constructed for each patient. The MICRO was then constructed with a forward stepwise selection from Elixhauser comorbidities and domain expert input. Indexes were used as covariates in multivariate logistic regression models with patient age, sex, and flap tissue type to predict complications following FTT. The area under the receiver operating characteristic curve and fivefold cross-validation classification accuracy was determined.A total of 5,595 patients were included. The final MICRO consists of seven variables (Charlson: 19; Elixhauser: 30). It had the highest area under the receiver operating characteristic curve (0.60) and accuracy (60.4%) of all indexes when predicting complications.The MICRO outperforms available patient comorbidity indexes at predicting complications following FTT with far fewer variables. Future studies could augment the MICRO with more granular or institutional data consisting of surgeon, donor-site, and recipient-site data to create a sharper risk-stratification tool for the plastic surgeon.

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Publication Details

Journal
Journal of Reconstructive Microsurgery
Published
2025-04-07
DOI
https://doi.org/10.1055/a-2576-0299
Primary Topic
Reconstructive Surgery and Microvascular Techniques
Type
article
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article

MICRO: Microsurgical Index for Complication Risk and Outcomes

Priscila Cevallos, Thomas Johnstone, Daniel Najafali, Clifford C. Sheckter et al.
Journal of Reconstructive Microsurgery
Reconstructive Surgery and Microvascular Techniques
article

MICRO: Microsurgical Index for Complication Risk and Outcomes

Priscila Cevallos, Thomas Johnstone, Daniel Najafali, Clifford C. Sheckter, Augustine Kang, Gordon K. Lee, Rahim Nazerali
article en

Abstract

Free tissue transfer (FTT) is determined by a multitude of patient and surgeon factors. However, no tool exists to quantify patient risk for complications following FTT. This study developed the microsurgical index for complication risk and outcomes (MICRO) to address this.Patients were queried from the 2007 to 2015 MarketScan Databases with CPT codes for FTT requiring microsurgical anastomosis. ICD-9 codes were used to query comorbidity and 90-day postoperative complication data for each patient. The Charlson and Elixhauser Comorbidity Indexes were constructed for each patient. The MICRO was then constructed with a forward stepwise selection from Elixhauser comorbidities and domain expert input. Indexes were used as covariates in multivariate logistic regression models with patient age, sex, and flap tissue type to predict complications following FTT. The area under the receiver operating characteristic curve and fivefold cross-validation classification accuracy was determined.A total of 5,595 patients were included. The final MICRO consists of seven variables (Charlson: 19; Elixhauser: 30). It had the highest area under the receiver operating characteristic curve (0.60) and accuracy (60.4%) of all indexes when predicting complications.The MICRO outperforms available patient comorbidity indexes at predicting complications following FTT with far fewer variables. Future studies could augment the MICRO with more granular or institutional data consisting of surgeon, donor-site, and recipient-site data to create a sharper risk-stratification tool for the plastic surgeon.

Journal of Reconstructive MicrosurgeryVol. 42(02)
Dartmouth College (US), University of Illinois Urbana-Champaign (US), Illinois College (US), Palo Alto University (US), University of California, Irvine (US), University of California, Irvine Medical Center (US), Stanford University (US)
Good health and well-being
Openalex Percentile: Top 88%
Reconstructive Surgery and Microvascular Techniques
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