FKBP51 Mediates Astrogliosis and Seizure Activities via NF-κB Signaling in Excitotoxic Brain Injury (S36.002)
The etiology and pathology of epilepsy remain elusive. We investigated the role of FK506-binding protein 51 (FKBP51, also called FKBP5) in mouse models of excitotoxic brain injury, and its involvement in reactive astrogliosis and NF-κB signaling.
Authors
- Chung‐Jiuan Jeng (ORCID: https://orcid.org/0000-0001-6271-5704)
- Yu-Ping Kang
- Yu‐Ling Gan (ORCID: https://orcid.org/0009-0007-3072-3049)
- Shang-Hsuan Lin
- I‐Hui Lee (ORCID: https://orcid.org/0000-0002-5344-6685)
- Weimin Huang (ORCID: https://orcid.org/0000-0002-6691-3369)
- Chia‐Chi Hung (ORCID: https://orcid.org/0000-0002-0914-6896)
- Jia-Zhen Zhou
- Yi‐Hsuan Lee (ORCID: https://orcid.org/0000-0002-3213-827X)
- Feng-Shiun Shie
- Pei-Chien Hsu
Institutions
- National Yang Ming Chiao Tung University (TW)
- National Health Research Institutes (TW)
- Taipei Veterans General Hospital (TW)
- Neuropsychiatric Research Institute (US)
- Czech Academy of Sciences, Institute of Physiology (CZ)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211326
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00