Pharmacokinetic-pharmacodynamic Modeling of Amantadine Extended-release Capsule Effects on Dyskinesia in Parkinson Disease (P7-5.028)
Evaluate pharmacokinetic/pharmacodynamic (PK/PD) relationships for the delayed- and extended-release (DR/ER) capsule formulation of amantadine in the treatment of levodopa-related dyskinesia in Parkinson disease.
Authors
- Rajesh Pahwa (ORCID: https://orcid.org/0000-0003-3176-6466)
- Mindy Grall
- Andrea E. Formella (ORCID: https://orcid.org/0000-0003-2737-7898)
- Jonathan Rubin (ORCID: https://orcid.org/0000-0003-4344-4587)
- Robert A. Hauser (ORCID: https://orcid.org/0000-0002-6369-1203)
- Roberto Goméni (ORCID: https://orcid.org/0000-0003-3916-9578)
- Zhao Wang (ORCID: https://orcid.org/0000-0003-3976-7439)
- Himanshu P. Upadhyaya
Institutions
- University of South Florida (US)
- University of Kansas Medical Center (US)
- Supernus Pharmaceuticals (United States) (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211309
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00