Simulating the impact of survival benefit-based liver transplant organ allocation
Our simulations predicted that survival benefit-based allocation would only increase posttransplant survival by an average of 18 days per recipient at the expense of a simulated increase in waitlist mortality of 400 deaths per year. In the current practice of liver transplantation, with the sickest-first allocation operating in a system where transplant physicians ration organs to maximize outcomes, the overall survival benefit is maintained and not compromised.
Authors
- Ezekiel Emanuel (ORCID: https://orcid.org/0000-0002-9796-5735)
- Cindy Delgado (ORCID: https://orcid.org/0000-0002-7156-0107)
- David Goldberg (ORCID: https://orcid.org/0000-0001-6514-9365)
- Catherine Blandon (ORCID: https://orcid.org/0000-0001-6414-6787)
- Binu V. John (ORCID: https://orcid.org/0000-0002-2002-9682)
- Peter P. Reese (ORCID: https://orcid.org/0000-0003-1440-069X)
- David E. Kaplan (ORCID: https://orcid.org/0000-0002-3839-336X)
Institutions
- University of Miami (US)
- Bruce W. Carter VA Medical Center (US)
- Philadelphia VA Medical Center (US)
- University of Pennsylvania (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Hepatology
- Published
- 2025-04-04
- DOI
- https://doi.org/10.1097/hep.0000000000001338
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00