Clinical Features and Outcomes of Central Nervous System Tumors with NTRK Gene Fusions (S29.005)

Our study describes the largest cohort of central nervous system (CNS) tumors with neurotrophic tyrosine receptor kinase (NTRK) gene fusions. We included 119 patients, detailing key demographic profiles, clinical characteristics and outcomes.

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000208692
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical Features and Outcomes of Central Nervous System Tumors with NTRK Gene Fusions (S29.005)

Michael J. Fisher, Uri Tabori, Holly Lindsay, Nicholas G. Gottardo et al.
Neurology
Glioma Diagnosis and Treatment
article

Clinical Features and Outcomes of Central Nervous System Tumors with NTRK Gene Fusions (S29.005)

Michael J. Fisher, Uri Tabori, Holly Lindsay, Nicholas G. Gottardo, Lauriane Lemelle, Nathan Robison, Jordan R. Hansford, Álvaro Lassaletta, Craig Erker, Lindsey M. Hoffman, Pouneh Amir-Yazdani, Stefan M. Pfister, Michal Zápotocký, David S. Ziegler, Birgit Geoerger, Daniel H. Orbach, François Doz, Alexander Edward Dela Cruz Drilon, Nada Jabado, Matthew Clarke, Audrey‐Anne Lamoureux, Sabine Mueller, Adam Resnick, Scott Raskin, Theodore Willis Laetsch, Sébastien Perreault, Christina Coleman, Christopher L. Moertel, Mélanie Alves, Pfaff Elke
article en

Abstract

Our study describes the largest cohort of central nervous system (CNS) tumors with neurotrophic tyrosine receptor kinase (NTRK) gene fusions. We included 119 patients, detailing key demographic profiles, clinical characteristics and outcomes.

NeurologyVol. 104(7_Supplement_1)
Cincinnati Children's Hospital Medical Center (US), University of Minnesota (US), Memorial Sloan Kettering Cancer Center (US), Children's Hospital of Philadelphia (US), Children's Hospital of Los Angeles (US), Cornell University (US), Charles University (CZ), Université Paris Sciences et Lettres (FR), Université Paris-Saclay (FR), Montreal Children's Hospital (CA), Great Ormond Street Hospital (GB), Izaak Walton Killam Health Centre (CA), Princess Margaret Hospital for Children (AU), Hospital for Sick Children (CA), Institut Gustave Roussy (FR), Centre Hospitalier Universitaire Sainte-Justine (CA), University of California System (US), Institute of Cancer Research (CA), University Hospital in Motol (CZ), Hospital Infantil Universitario Niño Jesús (ES), Phoenix Children's Hospital (US), SickKids Foundation (CA), Texas Children's Hospital (US), Children's Cancer Center (US), Perth Children's Hospital, University College London (GB), University of Cincinnati (US), Université de Montréal (CA), Institut Curie (FR)
Good health and well-being
Openalex Percentile: Top 90%
Glioma Diagnosis and Treatment
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