Comparing Efficacy and Safety of Levetiracetam Versus Phenytoin in Brain Injury: An Umbrella Review (P6-4.004)

Previous meta-analyses have compared the efficacy and safety of Levetiracetam versus Phenytoin in brain injury, producing varied results. This umbrella review aims to pool evidence from these meta-analyses to draw a definitive conclusion on which drug is safer and more effective for seizure prophylaxis after brain injury.

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000212034
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparing Efficacy and Safety of Levetiracetam Versus Phenytoin in Brain Injury: An Umbrella Review (P6-4.004)

Hassan Waseem, Aimen Zulfikar, Brandon Peter Lucke-Wold, Fnu Deepak et al.
Neurology
Pharmacological Effects and Toxicity Studies
article

Comparing Efficacy and Safety of Levetiracetam Versus Phenytoin in Brain Injury: An Umbrella Review (P6-4.004)

Hassan Waseem, Aimen Zulfikar, Brandon Peter Lucke-Wold, Fnu Deepak, Muhammad Sohail, Zain Ul Abideen, Azka Shahab, Syeda Nimra Qadri, Areeba Maryam, Sania Aimen, Zunaira Saeed, Esha Chaudhary, Sassi Abbasi
article en

Abstract

Previous meta-analyses have compared the efficacy and safety of Levetiracetam versus Phenytoin in brain injury, producing varied results. This umbrella review aims to pool evidence from these meta-analyses to draw a definitive conclusion on which drug is safer and more effective for seizure prophylaxis after brain injury.

NeurologyVol. 104(7_Supplement_1)
King Edward Medical University (PK), Rawalpindi Medical University (PK), Allama Iqbal Medical College (PK), Sindh Institute of Urology and Transplantation (PK), Bolan University of Medical and Health Sciences (PK), Shaheed Mohtarma Benazir Bhutto Medical University (PK), University of Florida (US), Dow University of Health Sciences (PK), Bahria University (PK)
Zero hunger
Openalex Percentile: Top 91%
Pharmacological Effects and Toxicity Studies
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Comparing Efficacy and Safety of Levetiracetam Versus Phenytoin in Brain Injury: An Umbrella Review (P6-4.004) — Hassan Waseem, Aimen Zulfikar, et al. · Neurology (2025) | TGRS Research Map | TGRS