Re-weighting MDS-UPDRS Part II and PDQ-39 Items to Detect Maximal Decline in Activities of Daily Living in Untreated Parkinson’s disease (P7-5.015)
This work used established methods to generate a composite scale from MDS-UPDRS-Part II and PDQ-39 items optimized for sensitivity to detect functional decline over 1-year.
Authors
- Jordan Dubow
- Suzanne Hendrix (ORCID: https://orcid.org/0000-0002-2374-7727)
- Lauren Powell (ORCID: https://orcid.org/0000-0003-3141-5551)
- Ellen Korol
- Fernanda Nagase
- Madeleine Crabtree (ORCID: https://orcid.org/0000-0001-5310-6595)
- Liana S. Rosenthal (ORCID: https://orcid.org/0000-0001-5140-3967)
- Vlad Coric
- Basia Rogula (ORCID: https://orcid.org/0000-0002-2115-8275)
- Michele Potashman (ORCID: https://orcid.org/0000-0001-7389-3354)
- Nick Kozauer
- Patrick O’Keefe (ORCID: https://orcid.org/0000-0002-5343-0130)
- Samuel P. Dickson (ORCID: https://orcid.org/0000-0002-4622-1349)
- Gilbert L’Italien
Institutions
- Biohaven Pharmaceuticals (United States) (US)
- TetraLogic Pharmaceuticals (United States) (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000208757
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00