Genetic Insights from Whole Exome Sequencing on IL-6 Signaling Genes in NMOSD: Unraveling Potential Mechanisms of Inflammation and Treatment Outcomes Driven by Anti-AQP4 Status and Ethnical backgrounds (S38.009)
To identify potential genetic modulators of IL-6 signaling within a serodiverse anti-AQP4 NMOSD cohort and examine the distribution of significant genetic variants across different ethnic backgrounds and their predicted effects on gene expression.
Authors
- Valéria Coelho Santa Rita Pereira (ORCID: https://orcid.org/0000-0002-7212-5043)
- Jéssica Vasques Raposo Vedovi
- Elielson Veloso da Silva (ORCID: https://orcid.org/0000-0002-5355-0538)
- Soniza Vieira Alves‐Leon (ORCID: https://orcid.org/0000-0002-1538-6730)
- Larissa Araújo Duarte (ORCID: https://orcid.org/0000-0003-2231-752X)
- Elisa Gouvea Gutman (ORCID: https://orcid.org/0000-0003-1060-1419)
- Andreza Lemos Salvio (ORCID: https://orcid.org/0000-0002-9256-2582)
- Renan Amphilophio Fernandes (ORCID: https://orcid.org/0000-0003-2505-039X)
- Helena Ferreira (ORCID: https://orcid.org/0009-0003-9975-9833)
- Anna Beatriz Scherer Vanzan
- Karla Pinto Coelho Fadel
Institutions
- Universidade Federal do Estado do Rio de Janeiro (BR)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000211584
- Primary Topic
- Protein Tyrosine Phosphatases
- Type
- article
- Field-Weighted Citation Impact
- 0.00