A Phase 1 Healthy Volunteer Dose Escalation to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Intravenous Human IgG1 Fc-F241A (NVG-2089) for the Treatment of CIDP (P4-11.015)

To evaluate the safety, PK, and PD of NVG-2089 following single and multiple ascending doses in healthy volunteers.

Authors

Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000208813
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
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article

A Phase 1 Healthy Volunteer Dose Escalation to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Intravenous Human IgG1 Fc-F241A (NVG-2089) for the Treatment of CIDP (P4-11.015)

Bill Avery, Joseph Wai-Hin Leung, Kurt A. Grimm, Pamela B. Conley et al.
1 links
Neurology
Monoclonal and Polyclonal Antibodies Research
article

A Phase 1 Healthy Volunteer Dose Escalation to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Intravenous Human IgG1 Fc-F241A (NVG-2089) for the Treatment of CIDP (P4-11.015)

Bill Avery, Joseph Wai-Hin Leung, Kurt A. Grimm, Pamela B. Conley, Jessica Bright, Sherry Mathew, Alan Glicklich, David D. Kim, Anoshie Ratnayake, Greg Coffey, Bella Oguno, Yvonne Coffey
article en

Abstract

To evaluate the safety, PK, and PD of NVG-2089 following single and multiple ascending doses in healthy volunteers.

NeurologyVol. 104(7_Supplement_1)
Good health and well-being
Openalex Percentile: Top 89%
Monoclonal and Polyclonal Antibodies Research
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