Single-cell Cerebrospinal Fluid Transcriptome Profiling Suggests Dysfunctional Boarder Associated Macrophages Underlying Progression Independent of Relapse Activity in Multiple Sclerosis (P6-1.011)
To characterize the cellular compartment of cerebrospinal fluid (CSF) in patients with relapsing multiple sclerosis (MS) with and without progression independent from relapse activity (PIRA) and infer differential cell-cell communication between groups.
Authors
- Monica Castellucci
- Federica Virla (ORCID: https://orcid.org/0009-0001-7346-9139)
- Elena Zenaro (ORCID: https://orcid.org/0000-0003-3928-6272)
- Stefano Ziccardi (ORCID: https://orcid.org/0000-0003-0426-7223)
- Damiano Marastoni (ORCID: https://orcid.org/0000-0003-0358-9431)
- Massimiliano Calabrese (ORCID: https://orcid.org/0000-0002-3362-7403)
- Daniela Anni (ORCID: https://orcid.org/0000-0002-5825-6303)
- Ermanna Turano (ORCID: https://orcid.org/0000-0002-0760-1787)
- Francesco Patanè (ORCID: https://orcid.org/0000-0003-2259-982X)
Institutions
- University of Verona (IT)
- University of Padua (IT)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000210990
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.00