SOX1-Positive Encephalitis Presenting as New-Onset Refractory Status Epilepticus (NORSE): A Rare Paraneoplastic Manifestation (P3-8.012)
Here we present a case of a female who presented with new onset refractory status epilepticus (NORSE). On investigation she found out to be suffering from lung carcinoma with no brain metastasis. She had NORSE as a paraneoplastic manifestation secondary to a rare positive SOX1 paraneoplastic antibody whose definitive therapy guidelines are still lacking. We highlight the importance of definitive therapy and need of treating underlying disease for complete recovery.
Authors
- Neetika Sharma
- Ashish K. Sharma (ORCID: https://orcid.org/0000-0002-1234-6039)
- Roopa Sharma
Institutions
- Rutgers, The State University of New Jersey (US)
- All India Institute of Medical Sciences Raipur (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000208792
- Citations
- 1
- Primary Topic
- RNA regulation and disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81