SOX1-Positive Encephalitis Presenting as New-Onset Refractory Status Epilepticus (NORSE): A Rare Paraneoplastic Manifestation (P3-8.012)

Here we present a case of a female who presented with new onset refractory status epilepticus (NORSE). On investigation she found out to be suffering from lung carcinoma with no brain metastasis. She had NORSE as a paraneoplastic manifestation secondary to a rare positive SOX1 paraneoplastic antibody whose definitive therapy guidelines are still lacking. We highlight the importance of definitive therapy and need of treating underlying disease for complete recovery.

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Publication Details

Journal
Neurology
Published
2025-04-07
DOI
https://doi.org/10.1212/wnl.0000000000208792
Citations
1
Primary Topic
RNA regulation and disease
Type
article
Field-Weighted Citation Impact
0.81
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article

SOX1-Positive Encephalitis Presenting as New-Onset Refractory Status Epilepticus (NORSE): A Rare Paraneoplastic Manifestation (P3-8.012)

Neetika Sharma, Ashish K. Sharma, Roopa Sharma
1 citations
Neurology
RNA regulation and disease
0.81
article

SOX1-Positive Encephalitis Presenting as New-Onset Refractory Status Epilepticus (NORSE): A Rare Paraneoplastic Manifestation (P3-8.012)

Neetika Sharma, Ashish K. Sharma, Roopa Sharma
article en
1 citations

Abstract

Here we present a case of a female who presented with new onset refractory status epilepticus (NORSE). On investigation she found out to be suffering from lung carcinoma with no brain metastasis. She had NORSE as a paraneoplastic manifestation secondary to a rare positive SOX1 paraneoplastic antibody whose definitive therapy guidelines are still lacking. We highlight the importance of definitive therapy and need of treating underlying disease for complete recovery.

NeurologyVol. 104(7_Supplement_1)
Rutgers, The State University of New Jersey (US), All India Institute of Medical Sciences Raipur (IN), All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 29%
RNA regulation and disease
0.81
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