Clinical Characteristics Associated With High Baseline Glial Fibrillary Acidic Protein (GFAP) and Neurofilament Light Chain (NfL) Levels in Patients With Anti-Aquaporin-4 Antibody-Positive (AQP4-Ab+) Neuromyelitis Optica Spectrum Disorder (NMOSD) Fro
Evaluate associations between baseline GFAP and NfL serum levels, clinical characteristics, and time to first adjudicated on-trial relapse in PREVENT (NCT01892345) and CHAMPION-NMOSD (NCT04201262).
Authors
- Dean M. Wingerchuk (ORCID: https://orcid.org/0000-0003-1608-8206)
- Kerstin R. Allen (ORCID: https://orcid.org/0009-0004-9286-6158)
- Makoto Kinoshita (ORCID: https://orcid.org/0000-0001-7012-6782)
- Jerome De Seze (ORCID: https://orcid.org/0000-0002-7197-7578)
- Jeffrey L. Bennett (ORCID: https://orcid.org/0000-0002-3346-1394)
- Jin Nakahara (ORCID: https://orcid.org/0000-0002-5858-0998)
- Jeannette N. Stankowski (ORCID: https://orcid.org/0000-0002-8481-2940)
- Stacey Lynn Clardy (ORCID: https://orcid.org/0000-0001-6600-9428)
- Sean Joseph Pittock (ORCID: https://orcid.org/0000-0002-6140-5584)
- Ruba Bou-Chahine
- Becky Jo Parks (ORCID: https://orcid.org/0009-0006-0881-975X)
Institutions
- Keio University (JP)
- WinnMed (US)
- AstraZeneca (Brazil) (BR)
- University of Utah Health Care (US)
- Alexion Pharma (Switzerland) (CH)
- University of Colorado Anschutz Medical Campus (US)
- The University of Osaka (JP)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000208779
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00