Acquired Hepatocerebral Degeneration: The Second Brain (HNS and CNS) (P8-5.029)
Acquired hepatocerebral degeneration (AHD) is a rare, underdiagnosed neurological syndrome in patients with chronic liver disease with limited treatment options. It presents with hypo and hyperkinetic movements. Its pathogenesis has been associated with manganese accumulation in the basal ganglia. It is often unnoticed under-diagnosed as a cause of cognitive impairment in patients with liver disease.
Authors
- Sol De Jesus (ORCID: https://orcid.org/0000-0003-3186-7857)
- Ereny Demian
- Papul Chalia
Institutions
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1212/wnl.0000000000208833
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00