Evaluation of Immunohistochemical Expression of Beta-catenin and E-cadherin as Epithelial–Mesenchymal Transition Markers in Colorectal Carcinoma – An Analytical Retrospective Study in a Tertiary Care Center
The findings suggest that abnormal expression of E-cadherin and beta-catenin is linked to poor tumor differentiation and higher rates of lymphovascular and nodal involvement. These markers may serve as potential biomarkers for assessing prognosis in colorectal carcinoma patients.
Authors
- Ramya Katta (ORCID: https://orcid.org/0000-0003-0910-0457)
- Aparna Chinnam
- Sindhura Nugala
- Madhavi Kolakonda
Institutions
- Government Medical College (IN)
- Guntur Medical College (IN)
- Government of Andhra Pradesh (IN)
- Government Medical College (IN)
Publication Details
- Journal
- International Journal of Applied and Basic Medical Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.4103/ijabmr.ijabmr_535_24
- Primary Topic
- Wnt/β-catenin signaling in development and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00