Personalized models of Beam/F3 targeting in transcranial magnetic stimulation for depression: Implications for precision clinical translation
This work establishes that scalp-based targeting can produce reliable targets in the dLPFC and be successfully evaluated using a combination of neuroimaging and E-field modeling in pragmatic, multisite applications. Importantly, this investigation also found that significant network effects occur early in treatment and that Beam/F3 targets can engage functional mechanisms in TMS.
Authors
- Kelvin O. Lim (ORCID: https://orcid.org/0000-0002-2390-7268)
- Paul E. Holtzheimer (ORCID: https://orcid.org/0000-0002-3552-3296)
- Noah S. Philip (ORCID: https://orcid.org/0000-0002-4889-8775)
- Leanne M. Williams (ORCID: https://orcid.org/0000-0001-9987-7360)
- Michelle R. Madore (ORCID: https://orcid.org/0000-0002-2351-7251)
- Divya Rajasekharan
Institutions
- Dartmouth College (US)
- VA Palo Alto Health Care System (US)
- Brown University (US)
- Providence VA Medical Center (US)
- Minneapolis VA Health Care System (US)
- University of Minnesota Medical Center (US)
- Minneapolis VA Medical Center (US)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1016/j.brs.2025.04.003
- Citations
- 5
- Primary Topic
- Transcranial Magnetic Stimulation Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.21
Funders
- National Science Foundation
- U.S. Department of Veterans Affairs
- Stanford Bio-X
- National Institute of Mental Health