Infrared Irradiation‐Assisted Green Approach for Pd‐Catalyzed Buchwald–Hartwig Amination
We report a novel and green approach for Pd-catalyzed Buchwald-Hartwig amination, assisted by Infrared (IR) irradiation under quasi-solvent-free conditions, in a nonanhydrous environment, and without the exclusion of air. The C-N coupling reactions, performed with a stoichiometric amount of cyclopentyl methyl ether, proceed with moderate-to-good yields using aryl iodides and bromides bearing both electron-donating and electron-withdrawing groups, along with a variety of secondary and primary amines.
Authors
- Gianluca M. Farinola (ORCID: https://orcid.org/0000-0002-1601-2810)
- Ambra Maria Fiore (ORCID: https://orcid.org/0000-0002-9882-0757)
- Angela Punzi (ORCID: https://orcid.org/0000-0001-5948-6373)
- Pietro Cotugno (ORCID: https://orcid.org/0000-0002-6487-9152)
- Davide Blasi (ORCID: https://orcid.org/0000-0002-6887-3364)
- Riccardo Ciciriello
Institutions
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Chemistry - A European Journal
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1002/chem.202500557
- Citations
- 2
- Primary Topic
- Catalytic Cross-Coupling Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali