COVID‐19 Challenges in Autoimmune Hepatitis Management: A Successful Outcome With Intravenous Immune Globulin (IVIg)
<b>Background:</b> Several autoimmune diseases, such as autoimmune hepatitis (AIH), can arise or become decompensated following COVID-19 infection or vaccination; however, there is a lack of data regarding the management of concurrent COVID-19 infection and autoimmune diseases. <b>Case Summary:</b> In this paper, we present a case of a 9-year-old boy with yellowish discoloration of the skin and sclera, abnormal liver function test, followed by positive qRT-PCR for SARS-CoV-2 and progressive bicytopenia. After a lack of response to corticosteroids, intravenous immune globulin (IVIg) was administrated and a decline in liver enzymes, total bilirubin, and direct bilirubin was observed. <b>Result and Discussion:</b> This case illustrates how IVIg significantly improved the AIH symptoms in the patient with positive qRT-PCR for the SARS-CoV-2 test. We hope our report encourages further research on therapeutic approaches for AIH concomitant with COVID-19.
Authors
- A. Cyrus Arman (ORCID: https://orcid.org/0009-0006-5737-5315)
- Parnian Khalili (ORCID: https://orcid.org/0000-0001-8443-3708)
- Fereshteh Karbasian (ORCID: https://orcid.org/0000-0003-2494-6231)
- Amirali Mashhadiagha (ORCID: https://orcid.org/0000-0002-8953-8979)
- Bita Geramizadeh (ORCID: https://orcid.org/0000-0002-4867-5686)
- Maryam Ataollahi (ORCID: https://orcid.org/0000-0003-1876-5266)
Institutions
- Iran University of Medical Sciences (IR)
- Shiraz University of Medical Sciences (IR)
Publication Details
- Journal
- Case Reports in Gastrointestinal Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/crgm/4446896
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00