Cytokine Storms in COVID-19, Hemophagocytic Lymphohistiocytosis, and CAR-T Therapy
This study of CS syndromes found distinct immune responses within each cohort. The distinct clinical patterns and outcomes associated with different CS etiologies emphasize the importance of early diagnosis and timely intervention.
Authors
- W Carol
- Parikh Bharat J (ORCID: https://orcid.org/0000-0002-5064-4272)
- Elena Franco‐Robles (ORCID: https://orcid.org/0000-0003-0345-7578)
- Paul Edelkamp (ORCID: https://orcid.org/0000-0001-5881-8292)
- Catherine John (ORCID: https://orcid.org/0000-0002-6057-2073)
- LK Jennifer
- C Krejci Caroline
- Scott E. Woodman (ORCID: https://orcid.org/0000-0002-1157-6991)
- Nisha S. Joseph (ORCID: https://orcid.org/0000-0003-4001-9622)
- P Priyadharshini
- Shete Sanjay
- Jason R. Westin (ORCID: https://orcid.org/0000-0002-1824-2337)
- F Mullally Sarah (ORCID: https://orcid.org/0000-0002-8202-1109)
- Fareed Khawaja (ORCID: https://orcid.org/0000-0003-4424-283X)
- Swaminathan P. Iyer (ORCID: https://orcid.org/0000-0002-1646-813X)
- Kelly Sharon Chien (ORCID: https://orcid.org/0000-0001-6024-1613)
- F Andrew
- Joanna-Grace Mayo Manzano (ORCID: https://orcid.org/0000-0001-6505-6425)
- Hiba Dagher (ORCID: https://orcid.org/0000-0002-8483-6977)
- Loretta J. Nastoupil (ORCID: https://orcid.org/0000-0001-6071-8610)
- Paolo Strati (ORCID: https://orcid.org/0000-0002-7445-1459)
- Sairah Ahmed (ORCID: https://orcid.org/0000-0001-7302-8299)
- Carmen de Juan (ORCID: https://orcid.org/0000-0002-4445-2514)
- Ajlan Al-Zaki
- Sandro J. Stoeckli (ORCID: https://orcid.org/0000-0001-6780-4765)
- Rishab Prakash
- Rudolf Lucas (ORCID: https://orcid.org/0000-0003-3805-8868)
- A Beckstead Ashley
- Vinod Ravi (ORCID: https://orcid.org/0000-0001-6080-9336)
- Cutherell Michael
- D Shiny Mary
- Sattva Swarup Neelapu (ORCID: https://orcid.org/0000-0003-1045-4914)
- P. Andrew Futreal (ORCID: https://orcid.org/0000-0001-8663-2671)
- Victor E. Mulanovich (ORCID: https://orcid.org/0000-0001-7028-4860)
- James P. Long (ORCID: https://orcid.org/0000-0001-5853-5938)
- Naval Daver
- Luis Malpica (ORCID: https://orcid.org/0000-0002-7082-1846)
- W. Eric
- Anath C. Lionel (ORCID: https://orcid.org/0000-0001-7174-7070)
- Mark Knafl (ORCID: https://orcid.org/0000-0002-3953-2173)
- Christopher R. Flowers (ORCID: https://orcid.org/0000-0002-9524-3990)
- Andrews Lee
- Tarek Hussein (ORCID: https://orcid.org/0000-0002-3919-5680)
- McGuire Mary
- L. J. W. Jack
- Yu Emily (ORCID: https://orcid.org/0009-0008-8070-7781)
- Hutcheson Kate
- Sharma Mohit R (ORCID: https://orcid.org/0000-0002-3124-9365)
- J. David (ORCID: https://orcid.org/0000-0003-4379-734X)
- John Webb
- P Sabitha
- Jia Wu (ORCID: https://orcid.org/0000-0001-9013-0818)
- T M Jeena
- T. Waalkes Phillip
- K. von der Mark
- B. M
- K. C.
- G.K. Christopher
- C Byrd John
- S Sloley Stephanie
- Ranjit Nair
- Dai Chihara
- G.M. Drew
- O S
- Martin Benjamin
- Bang L. K
- G. De Maria
- M. W.
- E. Paul
- Kyoichi Anai
- P Gauthier Nicholas
- W C
- Yao James C
- Barbosa Gregory R
- Zatorski Steven
- Aloia Thomas A
- Beird Hannah C
- Brock Kristy
- Dabaja Bouthaina
- Draetta Giulio
- Godoy Myrna
- Gunther Jillian
- Jin Jeff
- Kell Trey
- Musunuru Tejo
- Muthu Mayoora
- Rojas Hernandez Cristhiam
- Sajith Bilja
- Subbiah Ishwaria
- Turin Anastasia
- Unni Samir
- Vicknamparampil Benju
- Young Chingyi
- Abraham Sanu
- Bajwa Pratibha
Institutions
- The University of Texas MD Anderson Cancer Center (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.3455
- Citations
- 7
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 12.39
Funders
- Amgen
- Pfizer
- Gilead Sciences
- Celgene
- Agios Pharmaceuticals
- BeiGene
- Syndax Pharmaceuticals
- Seagen
- Daiichi-Sankyo
- Astellas Pharma
- Servier
- National Institutes of Health
- Genentech
- University of Texas MD Anderson Cancer Center
- Pharmacyclics
- National Cancer Institute
- National Center for Advancing Translational Sciences