Influenza vaccine effectiveness among primary and secondary school students in Shenzhen during the 2023/24 influenza season

During the winter influenza peaks, a total of 2689 ILI patients were collected from the two hospitals, with 58.61% of the participants vaccinated. Of the ILI patients, 761 (28.3%) were laboratory-confirmed influenza infection, with 76.7% being A(H3N2) and 22.8% B/Victoria. After adjusting for covariates, the adjusted VE (aVE) was 57.06% (95% CI, 48.59-64.13%). In the subtype/lineage and age subgroup analysis, influenza VE against B/Victoria was higher than A(H3N2), and decreased with age. More, influenza VE (aVE = 19.63% [95% CI, -29.13-49.98%]) against all subtypes/lineages were not statistically significant for the spring-summer peak. Overall, influenza vaccines provided significant protection against influenza-associated outpatient visits among students in Shenzhen during 2023/24 winter influenza season. The findings underscore the importance of maintaining high vaccination coverage.

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Publication Details

Journal
Emerging Microbes & Infections
Published
2025-04-07
DOI
https://doi.org/10.1080/22221751.2025.2490531
Citations
2
Primary Topic
Influenza Virus Research Studies
Type
article
Field-Weighted Citation Impact
2.71
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article

Influenza vaccine effectiveness among primary and secondary school students in Shenzhen during the 2023/24 influenza season

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2 citations
Emerging Microbes & Infections
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article

Influenza vaccine effectiveness among primary and secondary school students in Shenzhen during the 2023/24 influenza season

Huiqiao Gu, Yawen Jiang, Quan Lü, Shisong Fang, Fang Huang, Tiejian Feng, Hui Liu, Ying Sun, Xu Xie, Jiatong Sun, Jianhua Lu, Yuelong Shu, Min Jiang, Xiaozhen Chen, Xin Wang, Xiaoliang Wu
article en
2 citations

Abstract

During the winter influenza peaks, a total of 2689 ILI patients were collected from the two hospitals, with 58.61% of the participants vaccinated. Of the ILI patients, 761 (28.3%) were laboratory-confirmed influenza infection, with 76.7% being A(H3N2) and 22.8% B/Victoria. After adjusting for covariates, the adjusted VE (aVE) was 57.06% (95% CI, 48.59-64.13%). In the subtype/lineage and age subgroup analysis, influenza VE against B/Victoria was higher than A(H3N2), and decreased with age. More, influenza VE (aVE = 19.63% [95% CI, -29.13-49.98%]) against all subtypes/lineages were not statistically significant for the spring-summer peak. Overall, influenza vaccines provided significant protection against influenza-associated outpatient visits among students in Shenzhen during 2023/24 winter influenza season. The findings underscore the importance of maintaining high vaccination coverage.

Emerging Microbes & InfectionsVol. 14(1)
Sun Yat-sen University (CN), Shenzhen Center for Disease Control and Prevention (CN), Shenzhen Bao'an District People's Hospital (CN), Shenzhen Children's Hospital (CN)
Zero hunger
Openalex Percentile: Top 11%
Influenza Virus Research Studies
2.71
DOIOpen Access PDFOpenAlex
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