Comorbidity in Midlife and Cancer Outcomes
In this cohort study of 128 999 adults without a history of cancer, comorbidities in midlife were associated with the overall risk of cancer and more strongly associated with risk of multiple individual cancer types, with the direction of association differing across cancer types. These results may inform clinical management of patients at risk for cancer.
Authors
- Lee Jones (ORCID: https://orcid.org/0000-0002-8030-1211)
- Paul C. Boutros (ORCID: https://orcid.org/0000-0003-0553-7520)
- Chaya S. Moskowitz (ORCID: https://orcid.org/0000-0002-2850-8450)
- Jessica A. Lavery (ORCID: https://orcid.org/0000-0002-2746-5647)
Institutions
- Memorial Sloan Kettering Cancer Center (US)
- University of California, Los Angeles (US)
- Cornell University (US)
- University of Colorado Cancer Center (US)
- Weill Cornell Medicine (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.3469
- Citations
- 4
- Primary Topic
- Cancer survivorship and care
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- American Association for Cancer Research
- Memorial Sloan-Kettering Cancer Center
- National Cancer Institute