Deciphering Intercellular Communication of the Immune Landscape within Autosomal Dominant Polycystic Kidney Disease Microenvironment at Single-Cell Resolution

This comprehensive investigation provides valuable insights into the diverse landscapes of the ADPKD microenvironment at single-cell resolution, emphasizing MNPs, T cells, and fibroblasts. The study unveils complex interactions among these cell types, shedding light on an understanding of the immunological aspect of ADPKD and proposing potential therapeutic targets.

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Publication Details

Journal
Kidney Diseases
Published
2025-04-06
DOI
https://doi.org/10.1159/000545663
Primary Topic
Genetic and Kidney Cyst Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Deciphering Intercellular Communication of the Immune Landscape within Autosomal Dominant Polycystic Kidney Disease Microenvironment at Single-Cell Resolution

Qiuyu Li, Na Jiao, Fei Liu, Qi Shi et al.
Kidney Diseases
Genetic and Kidney Cyst Diseases
article

Deciphering Intercellular Communication of the Immune Landscape within Autosomal Dominant Polycystic Kidney Disease Microenvironment at Single-Cell Resolution

Qiuyu Li, Na Jiao, Fei Liu, Qi Shi, Jinglan Gu, Jiayi Song, Xiaoyi Li, Jianhua Mao
article en

Abstract

This comprehensive investigation provides valuable insights into the diverse landscapes of the ADPKD microenvironment at single-cell resolution, emphasizing MNPs, T cells, and fibroblasts. The study unveils complex interactions among these cell types, shedding light on an understanding of the immunological aspect of ADPKD and proposing potential therapeutic targets.

Kidney DiseasesVol. 11(1)
Fudan University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 92%
Genetic and Kidney Cyst Diseases
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