Diffusion levels for quantitative assessment of the apparent diffusion coefficient value in prostate MRI: a proof-of-concept bicentric study
Question It is still unclear how to incorporate quantitative information from diffusion-weighted imaging (DWI) into prostate MRI. Findings Combining DWI-derived diffusion levels (DLs) with the PI-RADS version 2.1 categorization reduced false positives while preserving high sensitivity for clinically significant prostate cancer. Clinical relevance DLs permit to easily account for ADC values of prostate lesions and, in turn, refine biopsy decisions.
Authors
- Lorenzo Cereser (ORCID: https://orcid.org/0000-0003-4480-8872)
- Pascal Baltzer (ORCID: https://orcid.org/0000-0002-3755-5398)
- Paola Clauser (ORCID: https://orcid.org/0000-0002-2365-6905)
- Miriam Isola (ORCID: https://orcid.org/0000-0002-6391-1720)
- Gianluca Giannarini (ORCID: https://orcid.org/0000-0002-6995-246X)
- Chiara Zuiani (ORCID: https://orcid.org/0000-0001-5132-3115)
- Maria De Martino (ORCID: https://orcid.org/0000-0002-0445-9578)
- Valeria Peruzzi
- Rossano Girometti (ORCID: https://orcid.org/0000-0002-0904-5147)
- Nina Pötsch (ORCID: https://orcid.org/0000-0001-6280-1012)
- Alessandro Crestani (ORCID: https://orcid.org/0000-0001-7443-8740)
Institutions
- University of Udine (IT)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- European Radiology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1007/s00330-025-11547-8
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Udine