Semaglutide reverses the chronic myopathy of hyperkalemic periodic paralysis: a case report
This is a promising alternative treatment for hyperPP. By directly acting on skeletal muscle both dependent and independent of insulin, Semaglutide and likely other Glucagon-like peptide agonists show promise as a novel once weekly option that may treat not just the hyperkalemic periodic paralysis but also the skeletal muscle atrophy in a multimodal way.
Authors
- Kenneth Brand
- Daniel L. Landry (ORCID: https://orcid.org/0000-0002-4775-2352)
- Gregory L. Braden (ORCID: https://orcid.org/0000-0003-1883-2609)
- Jeffrey Mulhern
Institutions
- Baystate Medical Center (US)
- Baystate Health (US)
Publication Details
- Journal
- BMC Nephrology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1186/s12882-025-04068-5
- Citations
- 2
- Primary Topic
- Ion channel regulation and function
- Type
- article
- Field-Weighted Citation Impact
- 1.61