Semaglutide reverses the chronic myopathy of hyperkalemic periodic paralysis: a case report

This is a promising alternative treatment for hyperPP. By directly acting on skeletal muscle both dependent and independent of insulin, Semaglutide and likely other Glucagon-like peptide agonists show promise as a novel once weekly option that may treat not just the hyperkalemic periodic paralysis but also the skeletal muscle atrophy in a multimodal way.

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Publication Details

Journal
BMC Nephrology
Published
2025-04-07
DOI
https://doi.org/10.1186/s12882-025-04068-5
Citations
2
Primary Topic
Ion channel regulation and function
Type
article
Field-Weighted Citation Impact
1.61
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article

Semaglutide reverses the chronic myopathy of hyperkalemic periodic paralysis: a case report

Kenneth Brand, Daniel L. Landry, Gregory L. Braden, Jeffrey Mulhern
2 citations
BMC Nephrology
Ion channel regulation and function
1.61
article

Semaglutide reverses the chronic myopathy of hyperkalemic periodic paralysis: a case report

Kenneth Brand, Daniel L. Landry, Gregory L. Braden, Jeffrey Mulhern
article en
2 citations

Abstract

This is a promising alternative treatment for hyperPP. By directly acting on skeletal muscle both dependent and independent of insulin, Semaglutide and likely other Glucagon-like peptide agonists show promise as a novel once weekly option that may treat not just the hyperkalemic periodic paralysis but also the skeletal muscle atrophy in a multimodal way.

BMC NephrologyVol. 26(1)
Baystate Medical Center (US), Baystate Health (US)
Openalex Percentile: Top 18%
Ion channel regulation and function
1.61
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Semaglutide reverses the chronic myopathy of hyperkalemic periodic paralysis: a case report — Kenneth Brand, Daniel L. Landry, et al. · BMC Nephrology (2025) | TGRS Research Map | TGRS