Comparing Durvalumab, Olaparib, and Cediranib Monotherapy, Combination Therapy, or Chemotherapy in Patients with Platinum-Resistant Ovarian Cancer with Prior Bevacizumab: The Phase II NRG-GY023 Trial
In patients with PROC with prior bevacizumab, all experimental arms failed to reach the primary objective of improving PFS compared with SOC.
Authors
- Koji Matsuo (ORCID: https://orcid.org/0000-0002-6232-8701)
- Elise C. Kohn (ORCID: https://orcid.org/0000-0002-8631-9762)
- Peter G. Rose (ORCID: https://orcid.org/0000-0003-2676-0166)
- John K. Chan (ORCID: https://orcid.org/0000-0003-3379-6829)
- Mariam M. AlHilli (ORCID: https://orcid.org/0000-0002-8494-5591)
- Christina Washington (ORCID: https://orcid.org/0000-0002-2482-8860)
- David Scott Miller (ORCID: https://orcid.org/0000-0002-8215-5887)
- Leslie Bradford (ORCID: https://orcid.org/0000-0001-6954-6712)
- Joyce F. Liu (ORCID: https://orcid.org/0000-0003-3888-3972)
- Kerry J. Rodabaugh (ORCID: https://orcid.org/0000-0002-8884-7083)
- Jung‐Min Lee (ORCID: https://orcid.org/0000-0003-1280-5909)
- Kathleen N. Moore (ORCID: https://orcid.org/0000-0002-5803-0718)
- Jean Siedel (ORCID: https://orcid.org/0000-0002-2596-3634)
- Austin Miller (ORCID: https://orcid.org/0000-0001-9739-8462)
- Christa Irene Nagel (ORCID: https://orcid.org/0000-0001-6454-6246)
- Veena S. John
- Andrea O’Shea
- Elizabeth Hopp (ORCID: https://orcid.org/0000-0002-0577-0501)
- Christopher B. Morse (ORCID: https://orcid.org/0000-0002-0155-4246)
- Chirag A. Shah
Institutions
- Sutter Health (US)
- University of Southern California (US)
- Gynecologic Oncology Group (US)
- Roswell Park Comprehensive Cancer Center (US)
- University of Minnesota (US)
- Northwell Health (US)
- Froedtert Hospital (US)
- Cleveland Clinic (US)
- Medical College of Wisconsin (US)
- University of Michigan (US)
- Allegheny General Hospital (US)
- New England Cancer Specialists (US)
- Sarah Cannon (US)
- MaineHealth (US)
- USC Norris Comprehensive Cancer Center (US)
- Dana-Farber Cancer Institute (US)
- Michigan Center for Translational Pathology (US)
- Metro-Minnesota Community Oncology Research Consortium (US)
- National Cancer Institute (MY)
- National Cancer Institute (US)
- University of Oklahoma Health Sciences Center (US)
- The Ohio State University (US)
- Case Western Reserve University (US)
- University of Nebraska Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
- University of Oklahoma (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1158/1078-0432.ccr-24-3877
- Citations
- 5
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 8.49