Astrocyte-Derived Extracellular Vesicles Alleviate Optic Nerve Injury Through Remodeling of Retinal Microenvironmental Homeostasis
We discovered that ADEVs play a neuroprotective role in optic nerve injury. Our findings provide a new cell-free therapeutic strategy for optic neuropathy.
Authors
- Wencan Wu (ORCID: https://orcid.org/0000-0001-7576-3019)
- Shihan Song (ORCID: https://orcid.org/0000-0002-9429-5297)
- Zhonghao Yu (ORCID: https://orcid.org/0009-0006-4702-2700)
- Guiqiong He
- Zai‐Long Chi
- Lili Chen (ORCID: https://orcid.org/0000-0002-9965-8990)
- Senmiao Zhu (ORCID: https://orcid.org/0000-0002-7644-5773)
Institutions
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
- Zhejiang Lab (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1167/iovs.66.4.16
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61