Effect of Photobiomodulation Therapy in an In vitro Model of Lung Adenocarcinoma
Aims: To evaluate the dosimetric parameters and biological effects of photobiomodulation in an in vitro model of urethane-induced lung adenocarcinoma.Specifically, to quantify inflammatory mediators (IL-6, IL-8, IL-10, IL-1, and IFN-) and assess the functional activity of BEAS-2B cells incubated with urethane and irradiated with low-level laser therapy (LLLT) at two energy densities (3 J and 7.5 J).Study Design: An experimental in vitro study using BEAS-2B bronchial epithelial cells exposed to urethane and treated with LLLT at 660 nm.
Authors
- Kelly Gomes Santana (ORCID: https://orcid.org/0000-0002-0070-9576)
- Flávio Aimbire (ORCID: https://orcid.org/0000-0002-4290-541X)
- Renata Kelly da Palma (ORCID: https://orcid.org/0000-0002-4799-0385)
- Cíntia Estefano Alves
- Tawany Gonçalves Santos (ORCID: https://orcid.org/0000-0001-7126-321X)
- Maria Cristina Chavantes (ORCID: https://orcid.org/0000-0002-8625-5076)
- Cinthya Cosme Gutierrez Duran (ORCID: https://orcid.org/0000-0001-9055-1524)
- Ana Paula Ligeiro de Oliveira (ORCID: https://orcid.org/0000-0001-6089-5107)
- Stella Regina Zamunér (ORCID: https://orcid.org/0000-0002-4694-7617)
- José Antônio Silva (ORCID: https://orcid.org/0000-0001-6904-9185)
- Rodrigo Labat Marcos
- S. Kamei
- Juliana R. P. de B. Hironaka
- Keilla Santos Soares Barros
Institutions
- Universitat de Vic - Universitat Central de Catalunya (ES)
- Universidade Nove de Julho (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Published
- 2025-04-07
- DOI
- https://doi.org/10.9734/ajrnh/2025/v8i1192
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo