Capsid and genome damage are the leading inactivation mechanisms of aerosolized porcine respiratory coronavirus at different relative humidities

Indoor environments can impact the stability of respiratory viruses, which can then affect the transmission rates. The mechanisms of how relative humidity (RH) affects virus infectivity still remain unclear. This study found RH inactivates porcine respiratory coronavirus by damaging its capsid and genome. The finding highlights the potential role of controlling indoor RH levels as a strategy to reduce the risk of coronavirus transmission.

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Publication Details

Journal
Applied and Environmental Microbiology
Published
2025-04-07
DOI
https://doi.org/10.1128/aem.02319-24
Citations
1
Primary Topic
Infection Control and Ventilation
Type
article
Field-Weighted Citation Impact
1.52

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article

Capsid and genome damage are the leading inactivation mechanisms of aerosolized porcine respiratory coronavirus at different relative humidities

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1 citations
Applied and Environmental Microbiology
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article

Capsid and genome damage are the leading inactivation mechanisms of aerosolized porcine respiratory coronavirus at different relative humidities

P. S. Ganesh Subramanian, Vishal Verma, Joanna L. Shisler, Thanh H. Nguyen, Aijia Zhou, Salma El-Naggar
article en
1 citations

Abstract

Indoor environments can impact the stability of respiratory viruses, which can then affect the transmission rates. The mechanisms of how relative humidity (RH) affects virus infectivity still remain unclear. This study found RH inactivates porcine respiratory coronavirus by damaging its capsid and genome. The finding highlights the potential role of controlling indoor RH levels as a strategy to reduce the risk of coronavirus transmission.

Applied and Environmental MicrobiologyVol. 91(5)
University of Illinois Urbana-Champaign (US), Illinois College (US)
U.S. Environmental Protection Agency
Life in Land
Openalex Percentile: Top 20%
Infection Control and Ventilation
1.52
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