Identification and Exploration of Immunity‐Related Genes and Natural Products for Alzheimer's Disease Based on Bioinformatics, Molecular Docking, and Molecular Dynamics
PGF, GFAP, SST, GPI, and NFKBIA were identified for early AD diagnosis, associated with immune cells and pathways in AD brains. 7 promising natural compounds, including luteolin and stigmasterol, were screened for targeting these biomarkers.
Authors
- Guiyun Li (ORCID: https://orcid.org/0000-0003-1308-3864)
- Jiamin Liu (ORCID: https://orcid.org/0009-0006-2086-8167)
- Chang Ye Yale Wang (ORCID: https://orcid.org/0000-0003-0710-1827)
- Hongyan Wu (ORCID: https://orcid.org/0000-0001-9523-5707)
- Yue Li (ORCID: https://orcid.org/0000-0003-4091-1506)
- Hai Huang (ORCID: https://orcid.org/0000-0002-0000-6758)
- Jinhua Kang
- Pengpeng Liang
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/iid3.70166
- Citations
- 4
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.66
Funders
- Sanming Project of Medicine in Shenzhen