Tumor-colonizing <i>Pseudoalteromonas elyakovii</i> metabolically reprograms the tumor microenvironment and promotes breast ductal carcinoma
Despite the existing studies, the specific microbial factors that influence the occurrence and progression of breast cancer still remain unclear. Researchers have clarified the distinctive microbial profile related to ductal carcinoma, a common histological type of breast cancer, in order to identify tumor-specific microbes and their roles in tumorigenesis. With the tumor microbiome as the focus, the enrichment of <i>Pseudoalteromonas elyakovii</i> features accelerates the disease progression in patients with ductal carcinoma of the breast. This study reveals the initial role relationship and innovative findings between <i>Pseudoalteromonas elyakovii</i> and ductal carcinoma in the breast.
Authors
- Yuning J. Tang (ORCID: https://orcid.org/0009-0006-7037-2901)
- Mingxing Xu (ORCID: https://orcid.org/0000-0002-6579-5559)
- Qinghui Zheng (ORCID: https://orcid.org/0009-0008-3425-9260)
- Qiuran Xu (ORCID: https://orcid.org/0000-0003-2171-9279)
- Hongchao Tang (ORCID: https://orcid.org/0000-0001-5534-4837)
- Yaoqiang Du (ORCID: https://orcid.org/0000-0002-9158-8174)
- Xin Zeng (ORCID: https://orcid.org/0000-0002-4180-3366)
- HaiFeng Su (ORCID: https://orcid.org/0000-0002-8302-9030)
- Xuli Meng (ORCID: https://orcid.org/0000-0002-5555-0232)
- Yang Zhang (ORCID: https://orcid.org/0000-0001-8592-5800)
- Chaopeng Zheng
- Yiyuan Pan (ORCID: https://orcid.org/0000-0001-7736-4951)
- Shuyan Liu (ORCID: https://orcid.org/0000-0002-5932-4857)
- Xiaozhen Liu (ORCID: https://orcid.org/0000-0003-4208-0961)
- Yajuan Zheng
- Zhihao Ye (ORCID: https://orcid.org/0009-0008-9373-7285)
- Jiancheng Mou
- Wenjuan Gui
Institutions
- Zhejiang Chinese Medical University (CN)
- Hangzhou Normal University (CN)
- Breast Cancer Research Foundation (US)
- Wenzhou Medical University (CN)
- Zhejiang Provincial People's Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- mBio
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1128/mbio.03873-24
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.84
Funders
- National Natural Science Foundation of China
- Department of Health of Zhejiang Province
- Major Scientific and Technological Project of Zhejiang Province