High‐Intensity Focused Ultrasound Devices for Skin Tightening: A Comparative Literature Review of Device Specifications

ABSTRACT Background Nonsurgical skin tightening using high‐intensity focused ultrasound (HIFU) and micro focused ultrasound (MFU) is a rapidly growing aesthetic procedure. However, a lack of comparative data on the technical specifications of leading devices (Ultherapy, Ultraformer, Liftera) hinders optimal treatment selection. This review addresses this gap. Materials and Methods For each device, a literature search (PubMed, Google Scholar, grey literature) focused on skin‐tightening applications. Inclusion criteria included articles published in English or Spanish after 2017 detailing technical specifications. Data extraction included regulatory approvals, ultrasound frequency, energy levels, treatment depths, thermal coagulation points per shot, and other treatment parameters. Results The review analyzed data from available publications and manufacturer documentation. Significant heterogeneity was identified across devices regarding ultrasound frequency, energy levels, treatment depths, and real‐time visualization capabilities. Ultherapy uniquely offers real‐time imaging. Due to limited published research, Ultraformer and Liftera data relied heavily on manufacturer information. Conclusion This literature review reveals substantial heterogeneity in the technical specifications of Ultherapy, Ultraformer, and Liftera for nonsurgical skin tightening. The lack of published literature for Ultraformer and Liftera highlights the need for further research to confirm manufacturer‐provided specifications and to establish clear evidence‐based guidelines for optimal treatment selection. The value of real‐time imaging in treatment optimization is also discussed.