Biallelic Variants in <scp><i>EPG5</i></scp> Gene Are Associated with Parkinson's Disease

Our results unveil a novel association between biallelic variants in EPG5 gene and PD, providing compelling initial evidence for the involvement of EPG5 and autophagy dysregulation in the development of PD. ANN NEUROL 2025;98:369-385.

Authors

Institutions

Publication Details

Journal
Annals of Neurology
Published
2025-04-07
DOI
https://doi.org/10.1002/ana.27242
Citations
8
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
10.83

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Biallelic Variants in EPG5 Gene Are Associated with Parkinson's Disease

Lin Wei, Jie Wang, Qian Xu, Runcheng He et al.
8 citations
Annals of Neurology
Autophagy in Disease and Therapy
10.83
article

Biallelic Variants in EPG5 Gene Are Associated with Parkinson's Disease

Lin Wei, Jie Wang, Qian Xu, Runcheng He, Hongxu Pan, Wei‐Qian Zeng, Xun Zhou, Sheng Zeng, Jinchen Li, Qiying Sun, Yuwen Zhao, Fu‐Lei Tang, Xinxiang Yan, Jifeng Guo, Beisha Tang, Zhenhua Liu, Dandan Wang, Xuejing Wang, Jian Qiu, Yao Zhou
article en
8 citations

Abstract

Our results unveil a novel association between biallelic variants in EPG5 gene and PD, providing compelling initial evidence for the involvement of EPG5 and autophagy dysregulation in the development of PD. ANN NEUROL 2025;98:369-385.

Annals of NeurologyVol. 98(2)
Central South University (CN), First Affiliated Hospital of University of South China (CN), Second Xiangya Hospital of Central South University (CN), First Affiliated Hospital of Zhengzhou University (CN), Xiangya Hospital Central South University (CN), University of South China (CN)
National Natural Science Foundation of China, China Postdoctoral Science Foundation, Natural Science Foundation of Hunan Province
Good health and well-being
Openalex Percentile: Top 1%
Autophagy in Disease and Therapy
10.83
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.