Effect of DMARD Therapy on Inflammatory Biomarkers and Disease Activity in Rheumatoid Arthritis Patients

The present study demonstrates that DMARD therapy significantly reduces inflammatory biomarkers and disease activity measures in patients with RA. A marked decline in CRP, ESR, and other inflammatory markers was observed, correlating with improvements in clinical parameters such as DAS28 and patient-reported outcomes. These findings highlight the efficacy of DMARDs in controlling systemic inflammation and disease progression, thereby improving the overall quality of life in RA patients. Further long-term studies are warranted to assess sustained remission and the potential for personalized treatment strategies.

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Publication Details

Journal
Journal of Orthopaedic Case Reports
Published
2025-01-01
DOI
https://doi.org/10.13107/jocr.2025.v15.i04.5526
Primary Topic
Rheumatoid Arthritis Research and Therapies
Type
article
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article

Effect of DMARD Therapy on Inflammatory Biomarkers and Disease Activity in Rheumatoid Arthritis Patients

Muzaffer Başak, Manish Khanna, Manish Dwivedi, Partha Pratim Das et al.
Journal of Orthopaedic Case Reports
Rheumatoid Arthritis Research and Therapies
article

Effect of DMARD Therapy on Inflammatory Biomarkers and Disease Activity in Rheumatoid Arthritis Patients

Muzaffer Başak, Manish Khanna, Manish Dwivedi, Partha Pratim Das, Krunal Thakrar, Hardik Kharbanda
article en

Abstract

The present study demonstrates that DMARD therapy significantly reduces inflammatory biomarkers and disease activity measures in patients with RA. A marked decline in CRP, ESR, and other inflammatory markers was observed, correlating with improvements in clinical parameters such as DAS28 and patient-reported outcomes. These findings highlight the efficacy of DMARDs in controlling systemic inflammation and disease progression, thereby improving the overall quality of life in RA patients. Further long-term studies are warranted to assess sustained remission and the potential for personalized treatment strategies.

Journal of Orthopaedic Case ReportsVol. 15(4)
Government Medical College (IN), Malabar Institute of Medical Sciences (IN), Tezpur Medical College & Hospital (IN), All India Institute of Medical Sciences Bhopal (IN), Government Medical College (IN)
Good health and well-being
Openalex Percentile: Top 89%
Rheumatoid Arthritis Research and Therapies
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