A Rare Autopsy Case Study of Accelerated Pulmonary and Extra Pulmonary Silicosis in Spleen in a Young Male

Silicosis is one of the most common occupational lung diseases in the world, caused by inhalation of silica dust (silica dioxide). Taking into account the intensity, time of exposure, onset and development of the disease, we found an autopsy case of accelerated pulmonary and extrapulmonary silicosis in which inorganic particles (presumably silica) were documented inside granulomas and macrophages of the spleen along with tubercular lesions in liver -systemic silicotuberculosis. With present this case to emphasize on the fact that cases of systemic silicosis are often underdiagnosed and to discuss the little understood pathophysiology of disseminated silicosis.