Dietary advanced glycation end-products exacerbate sarcopenia onset by activating apoptosis through PRMT1-mediated CRTC3 arginine methylation
PRMT1-mediated CRTC3 arginine methylation plays a critical role in AGE-induced sarcopenia and suggests potential therapeutic targets for preventing sarcopenia progression.
Authors
- Shu Shang
- Y Li
- Jiangxia Zheng (ORCID: https://orcid.org/0000-0001-7464-3154)
- Qiang Li (ORCID: https://orcid.org/0000-0003-1056-4152)
- Qin Wan (ORCID: https://orcid.org/0000-0001-7310-7704)
- Tianjin Huang
- Faxiu Chen
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Provincial People's Hospital (CN)
- Jiangxi Chest Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Cellular and Molecular Life Sciences
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1007/s00018-025-05657-1
- Citations
- 2
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 2.64
Funders
- Natural Science Foundation of Jiangxi Province
- Health Commission of Jiangxi Province