<scp>PF4</scp>‐dependent P‐selectin expression assay in comparison to the heparin‐induced platelet activation assay for the diagnosis of heparin‐induced thrombocytopenia

These findings suggest that the PEA is a promising functional test for HIT laboratory diagnostics based on the relatively high sensitivity; however, further studies are needed to validate its clinical applicability.

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Publication Details

Journal
Transfusion
Published
2025-04-07
DOI
https://doi.org/10.1111/trf.18242
Primary Topic
Heparin-Induced Thrombocytopenia and Thrombosis
Type
article
Field-Weighted Citation Impact
0.00

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article

PF4‐dependent P‐selectin expression assay in comparison to the heparin‐induced platelet activation assay for the diagnosis of heparin‐induced thrombocytopenia

Brian R. Curtis, Leendert Porcelijn, Rick Kapur, Masja de Haas et al.
Transfusion
Heparin-Induced Thrombocytopenia and Thrombosis
article

PF4‐dependent P‐selectin expression assay in comparison to the heparin‐induced platelet activation assay for the diagnosis of heparin‐induced thrombocytopenia

Brian R. Curtis, Leendert Porcelijn, Rick Kapur, Masja de Haas, Romy Meier, Anne-Tess C. Jolink, Suzanne Hofstede‐van Egmond, Michelle Kempe
article en

Abstract

These findings suggest that the PEA is a promising functional test for HIT laboratory diagnostics based on the relatively high sensitivity; however, further studies are needed to validate its clinical applicability.

TransfusionVol. 65(5)
Leiden University Medical Center (NL), Sanquin (NL), Versiti Blood Center of Wisconsin (US), Amsterdam University Medical Centers (NL), University of Amsterdam (NL)
Stichting Sanquin Bloedvoorziening
Quality Education
Openalex Percentile: Top 88%
Heparin-Induced Thrombocytopenia and Thrombosis
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