Identification and expression profile analysis of circRNAs associated with goat uterus with different fecundity during estrous cycle

Based on the analysis, we have established the expression profiles of circRNAs during the follicular and luteal phases, respectively. Furthermore, using various analytical methods and data from high- and low-yield experimental control groups over different periods, we have identified multiple circRNAs that affect the high reproductive capacity of goats. Through enrichment analysis of the host genes of these circRNAs, we have discovered several key candidate genes. These findings provide fundamental data for the study of the molecular mechanisms underlying the fecundity of goats and pave the way for future genetic improvement strategies.

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Publication Details

Journal
BMC Genomics
Published
2025-04-07
DOI
https://doi.org/10.1186/s12864-025-11489-x
Citations
3
Primary Topic
Circular RNAs in diseases
Type
article
Field-Weighted Citation Impact
2.42

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article

Identification and expression profile analysis of circRNAs associated with goat uterus with different fecundity during estrous cycle

Meiying Fang, Mingxing Chu, Xiaoyun He, Lin Tao et al.
3 citations
BMC Genomics
Circular RNAs in diseases
2.42
article

Identification and expression profile analysis of circRNAs associated with goat uterus with different fecundity during estrous cycle

Meiying Fang, Mingxing Chu, Xiaoyun He, Lin Tao, Yufang Liu, Xiaolong Du
article en
3 citations

Abstract

Based on the analysis, we have established the expression profiles of circRNAs during the follicular and luteal phases, respectively. Furthermore, using various analytical methods and data from high- and low-yield experimental control groups over different periods, we have identified multiple circRNAs that affect the high reproductive capacity of goats. Through enrichment analysis of the host genes of these circRNAs, we have discovered several key candidate genes. These findings provide fundamental data for the study of the molecular mechanisms underlying the fecundity of goats and pave the way for future genetic improvement strategies.

BMC GenomicsVol. 26(1)
Chinese Academy of Agricultural Sciences (CN), China Agricultural University (CN)
National Natural Science Foundation of China, Chinese Academy of Agricultural Sciences, Agricultural Science and Technology Innovation Program
Zero hunger
Openalex Percentile: Top 12%
Circular RNAs in diseases
2.42
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