Synthesis of New Axially Coumarin Disubstituted Silicon(IV) Phthalocyanines, Investigation of their DNA-Binding Properties and Inhibitory Activities on Ache and Buche
The combined singlet oxygen generation, DNA binding, and enzyme inhibition data underscore the potential of these SiPc-coumarin derivatives as multifunctional agents for PDT and neuroprotective applications such as Alzheimer's disease (AD).
Authors
- Özkan Danış (ORCID: https://orcid.org/0000-0003-1781-0520)
- Mehmet Salih Ağırtaş (ORCID: https://orcid.org/0000-0003-1296-2066)
- Bahattin Yalçın (ORCID: https://orcid.org/0000-0003-4448-1101)
- Furkan Meletli
- Ahmet Güneş (ORCID: https://orcid.org/0000-0003-0966-4025)
Institutions
- Van Yüzüncü Yıl Üniversitesi (TR)
- Naval Academy (TR)
- Marmara University (TR)
Publication Details
- Journal
- Current Topics in Medicinal Chemistry
- Published
- 2025-04-07
- DOI
- https://doi.org/10.2174/0115680266368541250311084659
- Citations
- 2
- Primary Topic
- Porphyrin and Phthalocyanine Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 1.04