GREEN SYNTHESIS OF MANGANESE NANOPARTICLES USING CURCUMA LONGA LINN. AND THEIR ANTIBACTERIAL ACTIVITY AGAINST COMMON URINARY TRACT PATHOGENS

The development of innovative and efficient methodologies for synthesizing Manganese nanoparticles (Mn-NPs) has garnered significant interest due to their widespread applications in consumer products. This study focuses on a biological approach to Mn-NP synthesis using extracts from Curcuma longa Linn. and an in-depth analysis of the synthesized nanoparticles. Characterization of the Mn-NPs was conducted through various analytical techniques, including UV-visible (UV-Vis) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and Fourier transform infrared (FTIR) spectroscopy. UV-Vis analysis revealed a maximum absorption peak at 460 nm, confirming the presence of Mn-NPs. Structural characterization indicated diffraction peaks corresponding to manganese nanocrystals, with crystallite sizes ranging from 40 to 90 nm. Further study by RT-PCR and invitro anti-dengue study has show a significant outcome. The antibacterial activity of the synthesized Mn-NPs was also evaluated, demonstrating significant sensitivity against all tested microorganisms.