Clinical management and oncologic outcomes of pure pleomorphic and florid lobular carcinoma in situ of the breast: Results from a large single institution experience
The 31.3 % upgrade ratio from pure P-/FLCIS to IC/DCIS recommends surgical excision. Axillary surgery should be omitted. Positive margins are strongly associated with LR. Surgery with negative margins is the mainstay of treatment. Larger multicentric studies are needed.
Authors
- Angelo Paolo Dei Tos (ORCID: https://orcid.org/0000-0002-1228-8940)
- Alberto Marchet (ORCID: https://orcid.org/0000-0002-8912-0505)
- Rocco Cappellesso (ORCID: https://orcid.org/0000-0002-0480-3412)
- Francesco Milardi (ORCID: https://orcid.org/0000-0003-2731-9794)
- Massimo Ferrucci (ORCID: https://orcid.org/0009-0006-4635-333X)
- Paola Del Bianco (ORCID: https://orcid.org/0000-0002-6597-0265)
- Daniele Passeri (ORCID: https://orcid.org/0009-0000-3772-9426)
Institutions
- University of Padua (IT)
- Istituto Oncologico Veneto (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1016/j.ejso.2025.110021
- Citations
- 5
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- Ministero della Salute