Mycobacterial antigen Ag85B restrains Hodgkin lymphoma tumor growth by inhibiting autophagy
Altogether, these results suggest that Ag85B inhibits HL growth via autophagy regulation. Current treatments for HL are associated with adverse events; therefore, Ag85B-mediated autophagy inhibition might be a promising strategy in to treat HL.
Authors
- Mei Yan
- Nuriding Hailiqiguli
- Yiping Shen (ORCID: https://orcid.org/0000-0001-5820-0839)
- Yingbin Yue
- Gulibaha Maimaiti
- Danlu Li
- Yu Liu (ORCID: https://orcid.org/0000-0001-6729-5702)
- Fan Chunyan
- Yunfei Zhang (ORCID: https://orcid.org/0000-0002-4698-5314)
- Yanfei Cheng (ORCID: https://orcid.org/0000-0002-9307-9066)
- Xuemei Wang (ORCID: https://orcid.org/0009-0000-7909-3171)
Institutions
- Boston Children's Hospital (US)
- Harvard University (US)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32604/or.2025.057842
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00