Effects of aerobic training on brachial artery flow-mediated dilation in healthy adults: a meta-analysis of inter-individual response differences in randomized controlled trials

The study found small improvements in <sub>ba</sub>FMD, suggesting an average 19.2% reduction in cardiovascular disease (CVD) risk, with some individuals-such as prehypertensive individuals-potentially experiencing even greater benefits from AT. However, a meta-analysis based on IIRD suggests that factors unrelated to AT predominantly explain <sub>ba</sub>FMD changes. Further research is needed to better understand response variability in individuals with cardiovascular risk factors, and longer studies are required to assess IIRD in the general population.

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Publication Details

Journal
BMC Sports Science Medicine and Rehabilitation
Published
2025-04-07
DOI
https://doi.org/10.1186/s13102-025-01124-3
Citations
2
Primary Topic
Cardiovascular and exercise physiology
Type
article
Field-Weighted Citation Impact
4.76

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article

Effects of aerobic training on brachial artery flow-mediated dilation in healthy adults: a meta-analysis of inter-individual response differences in randomized controlled trials

Kristina Drole, Armin Huso Paravlic
2 citations
BMC Sports Science Medicine and Rehabilitation
Cardiovascular and exercise physiology
4.76
article

Effects of aerobic training on brachial artery flow-mediated dilation in healthy adults: a meta-analysis of inter-individual response differences in randomized controlled trials

Kristina Drole, Armin Huso Paravlic
article en
2 citations

Abstract

The study found small improvements in <sub>ba</sub>FMD, suggesting an average 19.2% reduction in cardiovascular disease (CVD) risk, with some individuals-such as prehypertensive individuals-potentially experiencing even greater benefits from AT. However, a meta-analysis based on IIRD suggests that factors unrelated to AT predominantly explain <sub>ba</sub>FMD changes. Further research is needed to better understand response variability in individuals with cardiovascular risk factors, and longer studies are required to assess IIRD in the general population.

BMC Sports Science Medicine and RehabilitationVol. 17(1)
University of Ljubljana (SI), Masaryk University (CZ)
Javna Agencija za Raziskovalno Dejavnost RS, Univerza v Ljubljani
Good health and well-being
Openalex Percentile: Top 7%
Cardiovascular and exercise physiology
4.76
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Effects of aerobic training on brachial artery flow-mediated dilation in healthy adults: a meta-analysis of inter-individual response differences in randomized controlled trials — Kristina Drole, Armin Huso Paravlic · BMC Sports Science Medicine and Rehabilitation (2025) | TGRS Research Map | TGRS