Synthesis, Characterization and in vitro evaluation of Magnesium oxide Nanoparticles as Potential Anti-diabetic agents

The current study objective is to synthesize Mgo nanoparticles through green mediated means employing leaf extracts from Acalypha indica for biological purposes. The produced Mgo nanoparticles' optical, chemical and morphological characteristics were verified using UV–Vis spectroscopy, FT-IR, zeta potential, XRD and FE-SEM, in that order. Mgo nanoparticles' optical properties and functional groups were examined using UV visible absorption spectra and FT-IR analysis. The antibacterial evaluation of the generated Mgo nanoparticles was investigated using the disc diffusion method against microbial pathogens, including Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis, as well as Gram-negative bacteria Escherichia coli and Klebsiella pneumoniae. Amazing in vitro antibacterial, antioxidant and anti-diabetic properties of Mgo Nanoparticles synthesised using green assisted synthesis were noted. As a result, the current study concludes that environmentally safe, low-cost and green mediated magnesium oxide nanoparticles are the best materials for biological applications.

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Publication Details

Journal
Research Journal of Biotechnology
Published
2025-02-28
DOI
https://doi.org/10.25303/204rjbt1680176
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
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article

Synthesis, Characterization and in vitro evaluation of Magnesium oxide Nanoparticles as Potential Anti-diabetic agents

S. Chandana, K. Gnaneswari, Sabeeha Tabassum Kokkanti, Sai Kalyani C. Yogini et al.
Research Journal of Biotechnology
Nanoparticle-Based Drug Delivery
article

Synthesis, Characterization and in vitro evaluation of Magnesium oxide Nanoparticles as Potential Anti-diabetic agents

S. Chandana, K. Gnaneswari, Sabeeha Tabassum Kokkanti, Sai Kalyani C. Yogini, Chitturi Ch M. Kumari
article en

Abstract

The current study objective is to synthesize Mgo nanoparticles through green mediated means employing leaf extracts from Acalypha indica for biological purposes. The produced Mgo nanoparticles' optical, chemical and morphological characteristics were verified using UV–Vis spectroscopy, FT-IR, zeta potential, XRD and FE-SEM, in that order. Mgo nanoparticles' optical properties and functional groups were examined using UV visible absorption spectra and FT-IR analysis. The antibacterial evaluation of the generated Mgo nanoparticles was investigated using the disc diffusion method against microbial pathogens, including Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis, as well as Gram-negative bacteria Escherichia coli and Klebsiella pneumoniae. Amazing in vitro antibacterial, antioxidant and anti-diabetic properties of Mgo Nanoparticles synthesised using green assisted synthesis were noted. As a result, the current study concludes that environmentally safe, low-cost and green mediated magnesium oxide nanoparticles are the best materials for biological applications.

Research Journal of BiotechnologyVol. 20(4)
Openalex Percentile: Top 96%
Nanoparticle-Based Drug Delivery
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