Eutectogels: Recent Advances and Emerging Biological Applications

Abstract Eutectogels, a family of emerging materials, integrate the characteristics of deep eutectic solvents (DES) and gels, presenting unique application potential in biomedical engineering. However, the latest progress of eutectogels and their applications in the biomedical field remain to be summarized and refined. This review first introduces the composition of eutectogels and their unique properties generated by the interaction between DES and the gel matrix. Subsequently, the classifications and advantages of eutectogels are comprehensively discussed according to their cross‐linked preparation methods, including physical, chemical, and multiple cross‐linked. By analyzing the properties of eutectogels, such as mechanical performance, thermal properties, conductivity, injectability, and their structure‐function relationships, the application potential of eutectogels is overviewed. Then, the eutectogel's application prospects in biomedical engineering are elaborated in detail, including their application in drug delivery to improve drug stability and precise control release, enhancing curative effects and reducing side effects. Also, the functional utilization in tissue engineering, biosensing, bioadhesives, and related biomedical domains are comprehensively explored. Finally, existing challenges and prospective research directions of eutectogels are delineated.

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Publication Details

Journal
Advanced Functional Materials
Published
2025-04-07
DOI
https://doi.org/10.1002/adfm.202425778
Citations
29
Primary Topic
Hydrogels: synthesis, properties, applications
Type
article
Field-Weighted Citation Impact
17.15

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article

Eutectogels: Recent Advances and Emerging Biological Applications

Honghao Hou, L. Zhong, Chunyi Pu, Jiamian Zhan et al.
29 citations
Advanced Functional Materials
Hydrogels: synthesis, properties, applications
17.15
article

Eutectogels: Recent Advances and Emerging Biological Applications

Honghao Hou, L. Zhong, Chunyi Pu, Jiamian Zhan, Yi Hu, Wenhui Yang
article en
29 citations

Abstract

Abstract Eutectogels, a family of emerging materials, integrate the characteristics of deep eutectic solvents (DES) and gels, presenting unique application potential in biomedical engineering. However, the latest progress of eutectogels and their applications in the biomedical field remain to be summarized and refined. This review first introduces the composition of eutectogels and their unique properties generated by the interaction between DES and the gel matrix. Subsequently, the classifications and advantages of eutectogels are comprehensively discussed according to their cross‐linked preparation methods, including physical, chemical, and multiple cross‐linked. By analyzing the properties of eutectogels, such as mechanical performance, thermal properties, conductivity, injectability, and their structure‐function relationships, the application potential of eutectogels is overviewed. Then, the eutectogel's application prospects in biomedical engineering are elaborated in detail, including their application in drug delivery to improve drug stability and precise control release, enhancing curative effects and reducing side effects. Also, the functional utilization in tissue engineering, biosensing, bioadhesives, and related biomedical domains are comprehensively explored. Finally, existing challenges and prospective research directions of eutectogels are delineated.

Advanced Functional MaterialsVol. 35(36)
Southern Medical University (CN)
National Natural Science Foundation of China, National Key Research and Development Program of China
Openalex Percentile: Top 1%
Hydrogels: synthesis, properties, applications
17.15
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