Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines

Heterocyclic compounds, particularly aryl quinolines, are of paramount importance in pharmaceuticals, materials science, and agrochemicals owing to their diverse biological and physicochemical properties. However, traditional synthesis methods often rely on organic solvents and catalysts, which raise environmental and health concerns while requiring high energy inputs. This study addresses these challenges by applying the principles of green chemistry to develop a sustainable, efficient, and environmentally friendly synthetic route for aryl quinolines.

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Journal
ChemistryOpen
Published
2025-04-07
DOI
https://doi.org/10.1002/open.202400470
Primary Topic
Chemistry and Chemical Engineering
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines

Aliyeh Khajeh‐Khezri, Ignacio M. López‐Coca, Mohammad Qandalee, Mohammad Alikarami et al.
ChemistryOpen
Chemistry and Chemical Engineering
article

Exploring a Water–Ethyl Acetate System for the Efficient Synthesis of 4‐Aryl Quinolines

Aliyeh Khajeh‐Khezri, Ignacio M. López‐Coca, Mohammad Qandalee, Mohammad Alikarami, S. Izquierdo
article en

Abstract

Heterocyclic compounds, particularly aryl quinolines, are of paramount importance in pharmaceuticals, materials science, and agrochemicals owing to their diverse biological and physicochemical properties. However, traditional synthesis methods often rely on organic solvents and catalysts, which raise environmental and health concerns while requiring high energy inputs. This study addresses these challenges by applying the principles of green chemistry to develop a sustainable, efficient, and environmentally friendly synthetic route for aryl quinolines.

ChemistryOpenVol. 14(8)
Islamic Azad University of Garmsar (IR), Tarbiat Modares University (IR), Islamic Azad University Ilam Branch (IR), Universidad de Extremadura (ES)
Junta de Extremadura, European Regional Development Fund
Responsible consumption and production
Openalex Percentile: Top 93%
Chemistry and Chemical Engineering
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