Investigating the Therapeutic Potential of Sericin Nanofibers and Rice-Encapsulated Nanosericin for Psoriasis: Mechanistic Insights from a 3D Skin Model
ReS and nanosericin show significant therapeutic potential for psoriasis by targeting immunomodulatory pathways, modulating keratinocyte activity, reducing oxidative stress, and enhancing skin barrier restoration. Future research should optimize scalability, assess long-term safety, and explore synergistic effects with existing therapies, while further investigating molecular mechanisms for targeted treatment advancements.
Authors
- Tapanee Kanjanapruthipong
- Watcharamat Muangkaew
- Sumate Ampawong (ORCID: https://orcid.org/0000-0002-5378-2996)
- Kanchana Kengkoom (ORCID: https://orcid.org/0000-0003-0974-3479)
- Tipparat Thiangtrongjit
- Kamonpan Fongsodsri (ORCID: https://orcid.org/0000-0001-8707-9943)
- Onrapak Reamtong (ORCID: https://orcid.org/0000-0002-1154-6485)
- Pornanong Aramwit
- Passanesh Sukphopetch
Institutions
- Chulalongkorn University (TH)
- Rattana Bundit University (TH)
- Mahidol Oxford Tropical Medicine Research Unit (TH)
- The Royal College Of Anesthesiologists Of Thailand (TH)
- Office of the Royal Society
- Silpakorn University (TH)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/ijn.s508995
- Citations
- 2
- Primary Topic
- Silk-based biomaterials and applications
- Type
- article
- Field-Weighted Citation Impact
- 1.19