Induction of apoptosis and hypoxic stress in malignant melanoma cells via graphene-mediated far-infrared radiation
This study systematically elucidated that FIR exerts anti-tumor effects through multiple mechanisms, including inducing MM cell apoptosis, exacerbating hypoxic stress, and causing cell cycle arrest. The findings provide new insights and approaches for MM treatment and establish a theoretical foundation for the clinical application of FIR in cancer therapy.
Authors
- Wenxing Fu (ORCID: https://orcid.org/0000-0003-4579-1128)
- Binghui Wu (ORCID: https://orcid.org/0000-0003-4015-9991)
- Tianyi Xu (ORCID: https://orcid.org/0000-0003-4197-8163)
- Ziwen Chen (ORCID: https://orcid.org/0000-0001-6270-4431)
- Haijing Fu
- Chuan Ye (ORCID: https://orcid.org/0009-0001-3886-9567)
- Lina Chen (ORCID: https://orcid.org/0000-0002-4427-3719)
- Wumei Zhao
- Shijun Shan
Institutions
- Tan Kah Kee Innovation Laboratory (CN)
- Collaborative Innovation Center of Chemistry for Energy Materials (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1186/s12885-025-14031-0
- Citations
- 3
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- National Natural Science Foundation of China
- Xiamen University