Polarization Behavior of Fluorine-Labeled Glucose-Water Solution

Magnetic resonance imaging (MRI) with contrast agents has become an indispensable tool in medical imaging. When contrast agents such as $^3$He gas, $^{13}$C in pyruvic acid, or fluorine-labeled glucose (FDG) are used in vivo, sensitivity can increase by a factor of 10,000 or more, particularly when the nuclei are dynamically polarized. This report presents the results of the first dynamic polarization experiments involving fluorine and hydrogen in a glucose solution doped with TEMPO.

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Publication Details

Published
2025-04-04
DOI
https://doi.org/10.22323/1.472.0003
Primary Topic
Analytical Chemistry and Chromatography
Type
article
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article

Polarization Behavior of Fluorine-Labeled Glucose-Water Solution

G. Reicherz
3 links
Analytical Chemistry and Chromatography
article

Polarization Behavior of Fluorine-Labeled Glucose-Water Solution

G. Reicherz
article en

Abstract

Magnetic resonance imaging (MRI) with contrast agents has become an indispensable tool in medical imaging. When contrast agents such as $^3$He gas, $^{13}$C in pyruvic acid, or fluorine-labeled glucose (FDG) are used in vivo, sensitivity can increase by a factor of 10,000 or more, particularly when the nuclei are dynamically polarized. This report presents the results of the first dynamic polarization experiments involving fluorine and hydrogen in a glucose solution doped with TEMPO.

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Analytical Chemistry and Chromatography
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Polarization Behavior of Fluorine-Labeled Glucose-Water Solution — G. Reicherz · (2025) | TGRS Research Map | TGRS