Impact of genetic counseling and testing in individuals at high risk of familial Alzheimer's disease from Latin America: a non‐randomized controlled trial
We examined the adaptation and efficacy of a GCT protocol in LatAm for families at risk of ADAD.The GCT protocol mitigated psychological distress among at-risk ADAD families.The study confirms the protocol's cultural appropriateness and psychological safety.Future studies should explore the long-term psychological and public health impacts of GCT and use of GCT for treatment options.
Authors
- Pablo Bagnati (ORCID: https://orcid.org/0000-0003-2801-0537)
- Laura Ramirez Aguilar
- Ezequiel Surace (ORCID: https://orcid.org/0000-0001-8492-9578)
- Mauricio Arcos‐Burgos (ORCID: https://orcid.org/0000-0002-8529-0574)
- Randall John Bateman (ORCID: https://orcid.org/0000-0002-7729-1702)
- David Fernando Aguillon (ORCID: https://orcid.org/0000-0003-2283-536X)
- Francisco Lopera (ORCID: https://orcid.org/0000-0002-5238-0231)
- Ellen Ziegemeier
- Patricio Chrem
- L. Varela
- Ricardo Allegri (ORCID: https://orcid.org/0000-0001-7166-1234)
- Eric McDade (ORCID: https://orcid.org/0000-0002-6764-3866)
- Claudia Madrigal
- Cláudia Ramos (ORCID: https://orcid.org/0000-0002-0030-4501)
- Jorge J. Llibre‐Guerra (ORCID: https://orcid.org/0000-0002-2137-7750)
- M. Laura Fernández (ORCID: https://orcid.org/0000-0002-7973-1214)
- M. Castaño
- Gabriela Vigo
- Yudy Milena Leon
- Juan Pablo Picasso
- Gabriel Alberto VargasCuadros
- Erika Mariana Longoria
- Beatriz Mora Henao
- Juan Diego Barbaran
- Cristina Fernández (ORCID: https://orcid.org/0000-0001-9853-6257)
Institutions
- Universidad Pontificia Bolivariana (CO)
- Washington University in St. Louis (US)
- Universidad de Antioquia (CO)
- Instituto de Neurología Cognitiva (AR)
- Instituto Nacional de Neurología y Neurocirugía (MX)
Publication Details
- Journal
- Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/dad2.70102
- Citations
- 1
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Alzheimer's Association
- Foundation for Barnes-Jewish Hospital
- National Institute on Aging