Evaluation of a translational swine model of respiratory hypersensitivity induced by exposure to Phleum pratense pollen allergens
This work demonstrated that the immunization protocol in this experimental model can induce a type I respiratory hypersensitivity-like response mediated by antigen-specific IgE, with pathophysiological similarities to those of humans and prospective for translational basic and applied research.
Authors
- Juan Pablo Reyes‐Grajeda (ORCID: https://orcid.org/0000-0001-6498-3286)
- Axel Soto-Muñoz
- Carmen Ramírez-Estudillo
- César A. Reyes‐López (ORCID: https://orcid.org/0000-0002-9860-8983)
- Marco Antonio Vega‐López (ORCID: https://orcid.org/0000-0003-2245-5199)
- Mónica Luz Gómez-Esquivel
- Jessica Ledesma-Aparicio
- Gustavo Salazar-Guerrero
Institutions
- National Institute of Genomic Medicine (MX)
- Instituto Politécnico Nacional (MX)
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
Publication Details
- Journal
- Frontiers in Allergy
- Published
- 2025-04-07
- DOI
- https://doi.org/10.3389/falgy.2025.1557656
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.16